Chapter 3

Potential for Increased Investment Activity in 2025

U.S. Life Sciences Outlook 2025

2 Min Read

2 Min Read

Sales transactions of life sciences lab/R&D properties hit their lowest level in over a decade in 2024, largely due to high interest rates and weak supply-and-demand fundamentals.

CBRE Research projects marginally higher investment sales in 2025 for all commercial real estate sectors based on improved macroeconomic trends, lower interest rates and greater demand. Life sciences investment activity may see a slight uptick, although the sector’s surge in new supply in H1 2025 will be a headwind.

Figure 28: Annual Investment Volume of R&D Properties

Source: MSCI, Q4 2024.

While conventional office properties have seen cap rates jump to levels not seen in over a decade, cap rates for life sciences properties appeared to stabilize in 2024 and remained below levels a decade ago.

CBRE expects the 10-year Treasury yield to remain above 4% in 2025, suggesting that any potential decline in life sciences cap rates will be marginal.

Figure 29: Average Cap Rates for Office and R&D Properties

Source: MSCI, Q4 2024.

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Property Type

Life Sciences

We provide real estate investors with advisory, acquisition, debt & structured finance, valuation, property management, leasing, and disposition services for the full spectrum of life sciences facilities. CBRE’s expertise spans many life sciences categories and property types and leads the industry in managing highly-regulated space.